What demographic is most often affected by Takayasu's arteritis?

Takayasu's arteritis is an inflammatory disease that primarily affects large blood vessels, and it is notably more common in young women, particularly those between the ages of 15 and 40. This demographic is significantly more affected compared to other groups due to a combination of hormonal and genetic factors that may contribute to the pathogenesis of the disease. The condition often presents with symptoms such as fatigue, weight loss, and limb claudication, which may lead to important vascular complications if left untreated.

Other demographics, such as older men, children, and middle-aged adults, experience Takayasu's arteritis far less frequently. While it can occur across various age groups and sexes, the disproportionate prevalence in young women makes that demographic the most commonly affected. Understanding this characteristic helps in recognizing the typical patient profile and guiding clinicians in early diagnosis and management.